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자넷 옐렌 총재, '美경제전망과 한 가지 퍼즐' 연설(원문)

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※ 번역할 언어 선택

Speech to the Money Marketeers of New York University
New York, New York
By Janet L. Yellen, President and CEO, Federal Reserve Bank of San Francisco
For delivery April 26, 2007, 7:30 PM Eastern
Download and Print PDF Version (54KB)

The U.S. Economy: Prospects and a Puzzle Revisited

Good evening, everyone. It's a pleasure to be here with you. I know that the Money Marketeers have a long and rich history, and I’m honored to be among the many distinguished speakers who have addressed you over the years.

Tonight I plan to discuss the prospects for the U.S. economy. I’d like to return to a theme that I discussed in a speech a few months ago and that has been on my mind ever since. It concerns a puzzling economic development. The puzzle, as I put it then, was: Why is the labor market apparently going gangbusters, while growth in real GDP has turned in only a middling performance? The reason I’d like to revisit the puzzle is that, in the intervening period, its mystery has deepened: economic growth has unexpectedly slowed from “middling” to a crawl, while the unemployment rate has actually inched down and employment growth has remained robust. These and other recent developments have not dramatically changed my mainline forecast for the U.S. economy over the next year or so, but they have significantly increased the risks to the outlook, both for growth and inflation. While I’ve revised down my forecast for economic activity for the first half of 2007, I still expect to see a moderate pace in the second half of the year. At the same time, much of the news pertaining to the first quarter has been disappointing, and has raised the downside risk for growth. I continue to think that inflation is likely to edge down over the year, but, with labor markets appearing to have tightened further, rather than easing as I expected, the upside risks to this outlook have gotten bigger.

Before I begin to explain these points, let me note that my comments represent my own views and not necessarily those of my colleagues in the Federal Reserve System.

Going back a few months, the “middling” economic growth we had been seeing since the second quarter of last year was, in fact, not particularly surprising, considering the stance of monetary policy over the past couple of years. As this group well knows, the FOMC began raising the federal funds rate from a very low 1 percent back in mid-2004. After 17 stepwise increases, the funds rate reached 5¼ percent by June 2006, a level that I judged to be modestly restrictive. The Committee has held it at that level ever since.

The aim of these policy moves, to my mind, was to achieve an orderly slowing of growth to—and, for a time, below—its long-run trend. I anticipated that such a path for output growth would produce enough slack in the labor market to relieve potential inflationary pressures. Indeed, along with an expected reversal of transitory factors, a modest amount of slack would help to bring inflation down gradually to a more acceptable level than it had registered over the prior year.

Thus far, it looks as if things have shaped up pretty much as expected, at least as far as output is concerned. Real GDP growth registered 2 to 2½ percent rates in the final three quarters of 2006, somewhat below most estimates of the economy’s potential growth rate at the time, although growth this year appears, thus far, to be notably weaker. Most of the impetus for growth has come from a robust performance of personal consumption expenditures; indeed, with the impetus from past increases in equity and housing wealth, American consumers continued to spend more than they earned, and that resulted in a personal saving rate that fell even deeper into negative territory. The biggest drag on growth has come mainly from two sectors: residential construction and auto production. Since residential construction and the housing market more generally were—and are—such important factors in this story, let me take a few moments to discuss them in detail.

The cooling in the housing sector has, of course, been in part a response to a rise in financing costs. Although traditional fixed mortgage rates have actually fallen somewhat in recent years, rates on variable-rate mortgages have risen along with other short-term rates. I should note, however, that higher borrowing costs are not the only explanation; it’s likely that the recent cooling also is a necessary correction in house prices after years of phenomenal run-ups that ultimately proved to be unsustainable.

Residential investment grew quite strongly for several years, but the pace of growth began to weaken toward the end of 2005. Since then, growth has turned negative. Indeed, the level of residential investment spending declined almost 13 percent in real terms during 2006, with especially steep drops over the last two quarters. In fact, during each of those quarters, this sector alone—which represents only a little more than 5 percent of U.S. GDP—subtracted a hefty 1¼ percentage points from real GDP growth.

The more forward-looking indicators of conditions in housing markets have been mixed recently. Housing permits fell sharply from the summer of 2005 through the summer of 2006, but have flattened out since then. Sales of new and existing homes have continued to fall. House prices at the national level either have continued to appreciate, though at a much more moderate rate than before, or have fallen moderately, depending on the price index you look at. Looking ahead, futures markets are expecting small price declines in a number of metropolitan areas this year. Finally, and importantly, inventories of unsold new homes remain at very high levels, and these most likely will need to be worked off before we see a rebound in housing construction.

The latest twist in the housing sector story is the trouble involved with subprime mortgages. Hardly a day goes by without a news story about the financial difficulties now faced by borrowers and some large lenders in this market. Certainly, these problems warrant our close attention and raise significant issues for bank regulators and supervisors. After all, so-called exotic financing instruments—like interest-only loans, piggy-back loans, and loans with the possibility of negative amortization—were often designed to allow subprime borrowers into the market. So it will be important to find the balance that not only protects borrowers but also provides them opportunities to secure loans to buy homes and refinance mortgages.

The types of subprime loans that present the biggest problem are variable-rate mortgages. Delinquency rates on these loans have risen sharply since the middle of last year—they now exceed 11 percent—and there are indications that lenders are tightening credit standards for subprime borrowers. Looking more broadly across all types of mortgages, however—including prime borrowers and even subprime borrowers with fixed-rate loans—delinquency rates have remained low. While a tightening of credit to the subprime sector and foreclosures on existing properties have the potential to deepen the housing downturn, I do not consider it very likely that such developments will have a big effect on overall U.S. economic performance. I say this, in part, because these mortgages represent only a small part of the overall outstanding mortgage stock.

The bottom line for housing is that it has had a significant depressing effect on real GDP growth over the past six months or so. While I wouldn’t be surprised to see it begin to turn around in the latter half of this year, I also wouldn’t want to bet on it. In other words, housing remains a significant drag on the economy and a source of uncertainty in the outlook—much as it has for some time now.

However, two other developments have changed the risk profile of the economy. The first is something of a positive, in that the auto sector now appears poised to be less of a drag going forward. With the public demanding more fuel-efficient vehicles in the face of rising oil prices, U.S. automakers found themselves with large excess inventories of SUVs and trucks, so they cut back sharply on production last year. At this point, it appears that the adjustment to a lower level of inventories has been reached, and plans for auto production in the future look brighter.

The second development, unfortunately, is evidence of sluggishness in a new area—business investment in equipment, and, in particular, equipment outside of the reasonably strong high-tech area. The performance in non-high-tech equipment over the past nine months or so is surprising, since the business environment is marked by high profits, relatively favorable financing conditions, and growth in business output.

Part of the explanation for this sluggishness reflects what’s happening in construction—given the slump in housing, it should come as no surprise that investment in construction-related equipment has fallen off. However, even if we ignore this category, business investment has still been weak.

One commonly heard explanation is “caution in the boardroom,” as companies have felt the shocks of corporate scandals, terrorist attacks, war, and surging oil prices. While there may be some truth to this explanation, it does seem to fly in the face of the rapid growth we’ve seen in employment, which—given the cost and disruption of hiring and then having to lay off workers—also should be restrained by caution about the future.

Another explanation for weak business equipment investment that may be more likely and that is a bit more troubling is the possibility that the trend rate of productivity growth has slowed from its very fast pace over the last five years or so. For 2000-2005, the estimated trend rate was a blazing 3 percent, but for 2006, the actual data on productivity growth came in at a rate of only 1-1/2 percent. Discerning the extent to which these new lower numbers reflect a short-lived, cyclical phenomenon, a downshift in the trend rate or both, is neither obvious nor straightforward.

To explore this point, let me put a little context around U.S. productivity growth. From the mid-1970s through the mid-1990s, the trend rate of labor productivity in the nonfarm sector rose relatively slowly, at only about a 1½ percent annual rate on average. Then, in the second half of the 1990s, trend productivity appears to have accelerated sharply, to about a 2½ percent annual growth rate. This upward shift frankly came as a surprise and generated reams of research, not to mention journalism touting the “New Economy.” On the research front, there is a broad consensus that this acceleration was traceable to developments in information and communications technology. The tech industry itself registered remarkable productivity gains; furthermore, firms outside that industry benefited not only from increases in the new tech equipment but also from new “organizational capital.” By this, I mean things like business models, production processes, and a trained workforce.1 Take the so-called big-box retailers, like Wal-Mart and others, for example. Their success in using information technology to boost their retailing business did not merely involve buying computers. Instead, they had to consciously invest in knowledge about how to use information processing to better manage and, indeed, to reorganize their far-flung supply chains. In addition, when they reorganized processes, they also needed to retrain their workforce.

From 2000-2005, U.S. trend productivity growth is estimated to have accelerated again, as I mentioned, to around 3 percent. But productivity growth in the tech industry itself slowed down, and so did investment in tech equipment by firms that use it. Why, then, did productivity growth surge in this period, and what does the answer imply for productivity going forward? Here the stories are not so clear. One explanation begins with the notion that investment itself is disruptive, since firms have to divert resources to installing and learning to use the new capital. With less investment going on in the 2000s than in the late 1990s, there was less disruption, while, at the same time, firms continued to benefit from their earlier investments in reorganization. Taken together, these showed up as faster measured productivity growth.2 According to this explanation, if firms have slowed investment not only in IT but also in new organizational capital, then future productivity growth may also slow. But it also leaves open the possibility that firms will find further opportunities for organizational investments to benefit from fast information processing, and these investments may bear fruit again.

Another explanation for the productivity surge in 2000-2005 is that it reflected severe profit pressures that forced firms to cut costs by restructuring, engaging in mergers, and so on.3 Insofar as this explanation is at work, the cost-cutting resulted in one-time productivity gains and has not sown the seeds for faster productivity growth going forward.

Both explanations, then, are consistent with the possibility that trend productivity growth has slowed. However, I don’t want to overstate the degree of any possible slowing. We are still talking about trend growth going from about 3 percent in 2000 to 2005—the figure I cited earlier—to between 2 and 2½ percent now. So, productivity growth still would be reasonably strong, just not as strong as over the prior decade. As I said, a lower trend rate of productivity growth would help explain the sluggishness in business investment and put upward pressure on inflation for a time.

Beyond this, however, it could have implications for crucial fundamentals in the economy. It could lower the trend growth rate of real GDP; indeed, many forecasters are currently making modest downward adjustments to estimates of trend real GDP growth into a range of 2½ to 3 percent. Likewise, because a lower trend rate of productivity growth reflects a lower return to capital, it also implies a lower neutral level of the federal funds rate.

To sum up the story on output, real GDP advanced at moderate rates of 2 to 2½ percent in the final three quarters of last year. Recent monthly data show a more sluggish performance in the first quarter. My best guess is that real GDP will pick up the pace a bit in 2007, as growth in spending on housing and equipment turns up. Personal consumption expenditures should advance solidly, but, given the recent increases in energy prices and the reduced impetus from housing and equity wealth, the pace is likely to be noticeably slower than in 2006. Taking all of these factors into consideration, my forecast for real GDP growth in all of 2007 is modestly lower than it used to be, and I think my comments should make it clear that there are downside risks to this outcome, since it depends on near-term rebounds in both housing and business investment in equipment. So, as a policymaker, these are things I will keep a close eye on.

Moreover, even if these downside risks do not materialize and my “best guess” scenario for economic activity comes through, there is an additional layer of concern. Another key part of the desired “soft landing” would involve the emergence of enough slack in labor markets to help bring inflation down from where it currently stands. This is where I revisit the puzzle I posed at the beginning: if the economy is even more lackluster than before, why is the labor market still going gangbusters? The latest labor market data show payroll employment growing steadily and at a robust pace. Moreover, the unemployment rate has declined by three-quarters of a percentage point over the past year and a half and now stands at 4.4 percent; that rate suggests a degree of tightness in the labor market, because it is somewhat below common estimates of the rate that can be sustained in the long run without generating rising inflation. In other words, if labor markets are indeed on the tight side, and if they remain there, then there may be reason for concern about building inflationary pressures.

In my earlier look at the puzzle I discussed a set of benign possible explanations and a set of worrisome ones. For example, one benign, and likely, possibility is that part of the disconnect between the unemployment rate and output growth will be resolved by a little more patience. Labor markets adjust to output growth with a lag, and that lag is not always consistent over time. Another benign possibility is that the unemployment rate may be overstating the tightness of labor markets. There are a variety of other labor market indicators, and some suggest less tightness than the unemployment rate. For example, the Conference Board index of job market perceptions, which is based on a survey of households, suggests that labor markets are only very slightly on the tight side. Furthermore, measures of labor compensation do not all line up with tightness in labor markets. In particular, the employment cost index shows remarkably restrained increases of only 3 percent over the past year, about the same as the year before. These possibilities are much as they were a few months ago.

The worrisome possibilities that I considered back then, however, have become, unfortunately, more worrisome and could indicate building inflationary pressures. They revolve around the question of whether the apparent disconnect between labor markets and output reflects a misreading of how close output is to its long-run capacity. One possibility is that output is actually growing faster than the data show. In fact, there are some indications to that effect. An alternative measure of aggregate activity—one that looks at total income generated in the economy—suggests a higher level of activity than the traditional measure of GDP, which looks at production. If the income measure ends up being more accurate than the production measure, then the decline in the unemployment rate this year might not turn out to be surprising at all. Indeed, this would mean that both labor and product markets have been tight, which would add to our estimate of inflation pressures.

The other possibility is the one that I mentioned in connection with a possible slowdown in trend productivity growth: that is, that output’s long-run capacity may be lower than most economists have estimated. Slower growth in trend productivity would translate directly into slower growth in the trend growth rate of real GDP. The implication for inflation is that real GDP would have to grow at a slower rate than we previously thought was necessary to generate more slack.

In outlining these explanations for the disconnect between output and unemployment, my goal has been to highlight the added weight I am now giving to the worrisome side of things. At the same time, it’s important to note that I do not view these explanations as mutually exclusive—it is certainly possible that more than one could be in play. Moreover, I confess up front that I do not see a way to know which explanations carry more weight. What I do know is that the intensification on the worrisome side means that there is more uncertainty about the state of underlying inflationary pressures, so it will be especially important to monitor the incoming data very closely.

This uncertainty is a special concern when we look at the inflation data over the past year or so, which has been disappointing. Over the past year, our main measure of consumer inflation—the price index for personal consumption expenditures excluding food and energy, or the core PCE price index—has increased by 2.4 percent, which is higher than I would like to see.

While the possibility of slower underlying productivity growth raises uncertainties about how to interpret the puzzle and the associated implications for inflation, it also has a more direct and distinctly pessimistic implication for inflation. In particular, a slowdown in the trend rate of productivity growth means that firms’ trend unit labor costs will rise more rapidly unless compensation growth declines in tandem. Absent such a moderation in compensation growth, firms may adjust to more rapid cost pressures by passing them into the prices consumers pay for their products, placing upward pressure on core inflation, at least for a time. However, there is one mitigating factor: the markups firms set above unit labor costs are currently at very high levels. So, even if trend productivity growth has slowed, firms do have the room to absorb the increases in unit labor costs without raising the prices of their products. It remains to be seen how all of this will play out.

Furthermore, I believe there are two other important features of the economy that may well work in the direction of bringing inflation down. One of these is inflation expectations, which appear to have been well anchored for at least the past ten years or so, as the Fed has established its credibility with the public about both its commitment to and its competence in keeping inflation at low and stable rates. For example, in the face of the large oil price increases we've seen in recent years, this credibility shows up in the stability of survey and market measures of inflation expectations looking ten years ahead.4 Statistical analysis of the behavior of core inflation also lends some support to the view that inflation expectations have become anchored. Admittedly, this evidence is drawn from a relatively small sample, but it’s important because, if it holds up, it implies, that core inflation has become more likely to revert to its long-run average, which, over the past decade, is around 2 percent.

The second favorable feature, which I have already alluded to, is that core inflation may have been elevated partly because of some transitory factors that are likely to unwind over the next year or so. One is oil prices. Although core inflation, by definition, excludes energy prices, they still may affect core inflation to the extent that they are passed through to the prices of other goods and services. Energy prices have risen recently, but they are still well below their peaks of mid 2006. Over the two and a half years before that, energy prices more than doubled, and this probably put some upward pressure on core inflation. However, the effects of energy price changes on inflation are inherently temporary, and these upward pressures are likely to dissipate in 2007.

Another transitory factor is substantial upward pressures on rents, including imputed rents on owner-occupied housing that enter importantly into the calculation of the price of housing services, and therefore, consumer inflation. Over the last year, rents have been rising at an unusually rapid rate as potential buyers, increasingly being priced out of the housing market, have shifted from owning to renting. As rents adjust to more normal levels relative to house prices, I anticipate these increases will taper off, also lowering inflation.

To sum up my inflation forecast, then, I do expect the dissipation of upward pressure from energy prices and rents and the beneficial effects of anchored inflation expectations to bring inflation down modestly over 2007. However, I also am keenly aware that this pattern has yet to show up in the data. The inflation situation remains uncertain and, in particular, there are upside risks to my outlook, especially having to do with the situation in labor markets.

From my perspective as a monetary policymaker, I would say that, in these circumstances, with heightened risks to both growth and inflation, the best course for policy is watchful waiting. I think that the current stance of policy is likely to foster sustainable growth with a gradual ebbing of inflation over time. However, the inflation risks are skewed to the upside. For this reason, the FOMC’s press release following its March meeting notes that “the Committee’s predominant policy concern remains the risk that inflation will fail to moderate as expected.” I believe it’s important to remain focused on bringing inflation down gradually over time—not only because price stability is desirable in its own right, but also because a credible commitment to keeping inflation low and stable is necessary to ensure that inflation expectations remain well-anchored.

We cannot afford to go back to a world similar to the 1970s, where shocks that should have had only a transitory impact on inflation—whether due to oil prices, rents or movements in the dollar—shift longer-term inflation expectations and touch off a self-fulfilling wage-price spiral. The Fed’s commitment over the last two decades to keeping inflation low has fundamentally changed inflationary psychology and that has permitted both inflation and unemployment to be low and stable. Keeping inflationary expectations well anchored is essential to good outcomes for the economy overall.

At the same time that we must keep inflation moving down over time, we must be careful not to tighten too much, thereby posing unnecessary risks to continued expansion. An “asymmetric policy tilt” seems appropriate given the risks to inflation. However, the complexities of the current situation—including uncertainties concerning the behavior of output and employment, as well as growing downside risks to economic growth and the possibility that the neutral level of the funds rate has been lowered by a productivity slowdown—make it appropriate for policy to retain considerable flexibility in responding to emerging data. The statement thus emphasizes that “Future policy adjustments will depend on the evolution of the outlook for both inflation and economic growth, as implied by incoming information.” What all of these considerations add up to is that the stance of monetary policy will undoubtedly need to be adjusted in ways that are dictated by shifts in our forecasts for inflation, output, and employment in light of incoming data.

1. See, for example, Sandra Black and Lisa Lynch , “Measuring Organizational Capital in the New Economy” (2005), and Brynjolfsson et al. “Intangible Assets: Computers and Organizational Capital” (2002).

2. Stephen D. Oliner, Daniel E. Sichel, and Kevin J. Stiroh, “Explaining a Productive Decade,” Brookings Papers on Economic Activity (March 29-30, 2007), and Susanto Basu and John Fernald, “Information and Communications Technology as a General Purpose Technology: Evidence from U.S. Industry Data,” (forthcoming, German Economic Review).

3. See: Oliner et al., op. cit.; Dale W. Jorgenson, Mun S. Ho, and Kevin J. Stiroh, “A Retrospective Look at the U.S. Productivity Resurgence,” unpublished paper, 2007; John Fernald, David Thipphavong, and Bharat Trehan, “Will Fast Productivity Growth Persist?” FRBSF Economic Letter, 2007-09.

4. See Bharat Trehan and Jason Tjosvold, “Inflation Targets and Inflation Expectations: Some Evidence from the Recent Oil Shocks,” FRBSF Economic Letter, 2006-22, September 1, 2006. For a discussion of related issues, see John Williams, “Inflation in an Era of Well-Anchored Inflation Expectations,” FRBSF Economic Letter, 2006-27, October 13, 2006.

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위고비에 도전한 새 비만약 '에페' 가격은? [서울=뉴스핌] 김신영 기자 = 한미약품의 국산 비만 신약 '에페'가 위고비와 마운자로가 86%를 장악한 국내 비만치료제 시장에 뛰어든다. 후발주자인 만큼 자체 생산을 통한 가격 경쟁력과 국내 환자 임상 데이터, 기존 병·의원 영업망을 앞세워 선발 제품 중심의 처방 시장을 파고든다는 전략이다. 관건은 가격 이외의 경쟁력을 실제 처방 전환으로 연결할 수 있느냐다. 위고비와 마운자로는 글로벌 시장에서 이미 높은 인지도와 장기간의 처방 경험을 쌓은 데다 대표 임상에서 높은 체중 감량 효과를 제시했다. 에페가 연매출 1000억원 목표를 달성하려면 가격에 민감한 신규 수요를 확보하는 동시에 기존 GLP-1 치료제 사용자의 선택까지 끌어와야 한다. 17일 제약·바이오업계에 따르면 한미약품은 오는 10월 식품의약품안전처 품목허가를 목표로 에페(성분명 에페글레나타이드) 출시를 준비하고 있다. 허가 이후 연내 출시가 목표다. 한미약품 본사 전경 [사진=한미약품] ◆ 가격 경쟁력 갖췄지만…출시 이후 기존 제품 인하 변수 에페는 한미약품이 자체 개발한 주 1회 투여 글루카곤 유사 펩타이드(GLP-1) 계열 비만치료제다. 약물이 체내에서 오래 작용하도록 한 한미약품의 지속형 플랫폼 기술 '랩스커버리'가 적용됐다. 에페가 진입할 시장은 이미 선발주자 중심으로 2강 구도가 형성돼 있다. 의약품 시장조사기관 아이큐비아에 따르면 국내 비만치료제 시장은 2024년 2426억원에서 지난해 8195억원으로 1년 만에 3배 이상 확대됐다. 이 중 위고비와 마운자로 판매액은 각각 4833억원, 2209억원으로 두 제품이 전체 시장의 약 86%를 차지했다. 후발주자인 에페가 내세운 무기는 가격이다. 한미약품은 최종 공급가를 공개하지 않았지만 업계와 증권가에서는 4주 투약 기준 10만원대 가격이 거론된다. 현재 위고비의 시작용량인 0.25㎎의 4주분 공급가는 21만6000원, 마운자로의 시작용량인 2.5㎎은 27만8000원 수준이다. 한미약품이 가격 경쟁력을 확보할 수 있는 배경에는 자체 생산체제가 있다. 회사는 경기도 평택 바이오플랜트에서 에페를 직접 생산한다. 외부 생산 의존도를 낮춰 공급 안정성을 높이는 동시에 가격을 낮추겠다는 구상이다. 하지만 가격만으로 선발주자의 벽을 넘을 수 있을지는 미지수다. 국내에서 가장 먼저 출시된 비만치료제인 위고비는 마운자로의 국내 출시를 앞둔 지난해 용량별 차등가격제를 도입하면서 시작용량 공급가를 기존 37만2000원에서 21만6000원으로 약 42% 낮췄다. 경쟁 제품 등장에 맞춰 선발주자가 가격을 조정한 전례가 있는 만큼 에페 출시 이후 추가 가격 경쟁이 벌어질 가능성도 제기된다. 비만치료제의 핵심 경쟁력은 체중 감량 효과다. 한미약품이 공개한 에페 임상 3상 40주차 중간 결과에서 평균 체중 감소율은 9.75%였다. 체중이 5% 이상 감소한 환자는 79.42%, 10% 이상은 49.46%, 15% 이상은 19.86%였다. 선발 제품들은 글로벌 임상에서 더 높은 체중 감소율을 제시했다. 위고비는 비만 또는 과체중 성인 1961명을 대상으로 한 STEP 1 임상에서 68주 투여 후 평균 체중이 14.9% 감소했다. 체중이 5% 이상 줄어든 환자는 86.4%, 10% 이상은 69.1%, 15% 이상은 50.5%였다. 마운자로는 비만 또는 과체중 성인 2539명을 대상으로 한 'SURMOUNT-1' 임상에서 72주 후 평균 체중 감소율이 5mg 투여군 15.0%, 10mg 19.5%, 15mg 20.9%로 나타났다. 15mg 투여군에서는 70.6%가 체중을 15% 이상 줄였고, 56.7%는 20% 이상 감량했다. 다만 에페와 위고비, 마운자로의 임상은 투약 기간과 대상 환자, 용량과 시험 설계 등이 달라 체중 감소율을 단순 비교해 우열을 판단하기에 한계가 있다. 현재 공개된 에페의 임상 수치는 40주차 3상 중간 결과다. 한미약품 비만 신약 '에페' 로고 [사진=한미약품] ◆ 국내 환자 448명 임상으로 차별화, 브랜드·시장 경험은 숙제 이에 한미약품이 강조하는 에페의 차별점은 국내 환자를 대상으로 직접 확보한 임상 데이터다. 에페 임상 3상은 국내 성인 비만 환자 448명을 대상으로 실시했다. 위고비 역시 한국인을 포함한 아시아 환자 대상 임상을 진행했지만 에페는 3상 전체를 국내 비만 환자로 구성했다. 한미약품은 국내 환자로 구성된 임상을 통해 한국 진료현장에서 참고할 수 있는 데이터를 확보했다는 점을 차별화 요소로 내세운다. 다만 국내 환자 대상 임상이라는 사실 자체가 기존 치료제보다 높은 효능이나 안전성을 의미하는 것은 아니다. 임상에서 체질량지수(BMI) 30㎏/㎡ 미만 여성 환자의 평균 체중은 12.20% 감소했다. 한미약품은 이를 토대로 고도비만 환자뿐 아니라, 비만도가 낮거나 장기적인 체중 관리가 필요한 환자까지 처방 수요를 넓힐 수 있을 것으로 보고 있다. 한미약품은 에페가 GLP-1 비만치료제의 대표적인 부작용인 구역과 구토 등 위장관계 이상반응이 기존 제품 대비 낮다는 점도 내세우고 있다. 구역과 구토는 비만치료제의 투약을 중단하게 하는 요인으로 거론된다. 그러나 브랜드 인지도와 시장 경험에 있어서는 선발주자의 우위가 뚜렷하다. 위고비와 마운자로는 각각 노보 노디스크와 일라이 릴리라는 글로벌 대형 제약사의 제품으로, 해외에서 이미 대규모 판매와 처방 경험을 축적했다. 환자들의 실제 사용 경험과 장기 데이터가 쌓였다는 점도 후발주자인 에페가 단기간에 따라잡기 어려운 부분이다. 반면 한미약품은 국내 병·의원을 대상으로 구축한 영업망과 자체 생산능력을 갖추고 있다. 기존 영업망을 치료제 처방으로 연결할 수 있느냐가 후발주자의 한계를 극복할 변수가 될 것이라는 평가가 나온다. 한미약품은 에페를 연 매출 1000억원 이상 품목으로 육성한다는 목표를 세웠다. 목표 달성을 위해서는 가격 경쟁력 등 회사가 내세운 강점을 처방 확대로 연결할 수 있어야 한다.  한 업계 관계자는 "에페는 가격과 국내 환자 대상 임상 데이터에서 차별화 요소가 있지만 위고비와 마운자로는 높은 인지도와 처방 경험을 확보한 제품"이라며 "후발주자인 만큼 실제 진료 현장에서 의사와 환자의 선택을 얼마나 바꿀 수 있느냐가 시장 안착의 관건"이라고 봤다. sykim@newspim.com 2026-09-17 15:33
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李, 일정 최소화 '18일 회견' 준비 몰두 [서울=뉴스핌] 김미경 기자 = 이재명 대통령이 18일 기자회견을 하루 앞둔 17일 공식 일정을 최소화하고 회견 준비에 몰두했다. 이 대통령은 지난 14일부터 3일간 중앙아시아 5개국 정상과 연쇄 회담을 하고 1차 한-중앙아시아 정상회의를 주재하며 외교 일정으로 숨가쁘게 지냈다.  이 대통령이 기자회견 일정을 18일로 정한 것도 외교 일정을 모두 마무리하고 하루 정도 준비하는 시간이 필요하다는 판단을 한 것으로 보인다.  이 대통령은 이날 통상 목요일에 열던 수석보좌관회의도 없이 파티 비롤 국제에너지기구(IEA) 사무총장을 접견하는 일정만 소화한다.  이재명 대통령이 취임 1주녁 기자회견에서 주택공급을 위해 재건축·재개발도 속도를 내야한다고 말했다. [사진=청와대]  ◆청와대 "국민이 궁금한 국정 현안, 진솔하게 소통할 것" 이 대통령은 비롤 사무총장 접견 외 나머지 시간은 회견 준비에 쓸 것으로 예상된다. 이 대통령은 참모들에게서 분야별 핵심 쟁점과 추진 방향을 보고받고 예상 질문을 추려 답변을 거듭 다듬는 것으로 알려졌다. 회견은 18일 오전 10시 청와대 영빈관에서 열린다. 모두발언과 질의응답, 마무리 발언을 합쳐 90분가량 진행한다는 계획이다. 기자회견에는 내·외신 기자 150여 명이 참석한다. 질의응답은 정치·외교와 정책·경제 두 분야로 나눠 주제 제한 없이 진행하고 실시간 국민 댓글도 소개한다. 청와대는 회견 제목을 수식어 없이 '이재명 대통령 기자회견'으로 정했다. 회견장 배경막에는 '국민의 뜻, 국민의 삶, 더 살피겠습니다'라는 문구를 건다. 성기홍 청와대 홍보소통수석은 지난 15일 브리핑에서 "대통령의 확고한 개혁 의지와 민생 최우선 국정 기조, 더 단단한 국민 통합의 메시지를 전하는 자리가 될 것"이라고 했다. 이어 "국민이 궁금해하고 듣고 싶어 하는 국정 현안을 진솔하고 충실하게 소통하려 한다"고 설명했다. [서울=뉴스핌] 이건주 기자 = 8일 오전 서울 중구 하나은행 딜링룸에서 이재명 대통령 취임 1주년 기자회견 '대체불가 대한민국'이 생중계되고 있다. 2026.06.08 kunjoo@newspim.com ◆연임·공소취소·파병 정치 현안에 부동산·증시 민생 현안 산적  회견의 관심은 산적한 현안에 이 대통령이 과연 명확한 입장을 밝힐 것인지다. 특히 공소 취소와 연임 헌법 개정(개헌) 논란은 피할 수 없는 질문이다. 집권 여당인 더불어민주당은 '조작기소 특검법안'을 9월 중 처리하겠다고 예고했다. 특검에 공소취소 권한을 줄지가 핵심 쟁점이다. 이 대통령 사건 공소 취소를 앞장서 주장했던 김승원 의원이 법무부 장관 후보자로 지명됐고 민주당 주도로 국회 인사청문 경과보고서가 채택됨에 따라 야권의 공세는 더 거세졌다. 인사 검증 문제에 대한 언론의 질의도 예상된다. 용혜인 전 성평등가족부 장관 후보자는 자진사퇴했고 김승원 후보자는 '식약처 청탁 의혹'에 휩싸였다. 미국 요청에 따른 호르무즈 해협 파병 검토와 대미 투자 협상 관련 질문도 이 대통령에게는 고난도 문제다.  민생 현안으로는 부동산이 첫손에 꼽힌다. 정부는 취임 후 8·13 대책을 포함해 6차례 부동산 대책을 내놨다. 하지만 한국부동산원 집계에 따르면 서울 아파트 주간 매매 가격이 지난해 2월 첫째 주부터 83주 연속 올랐다. 문재인 정부 시절 세운 최장 기록(85주)에 바짝 다가섰다. 강남 3구 집값은 약세로 돌아섰지만 수도권 중저가 아파트값이 오르고 전세 매물 품귀와 월세 상승이 이어지고 있다. 부동산 정책 효과에 대한 논란이 적지 않다.  이재명 대통령이 8일 청와대 영빈관에서 취임 1주년 기자회견을 하고 있다. 2026.06.08 [사진=청와대] ◆이 대통령 "임기는 헌법상 명확하게 제한"…이번엔 어떤 답 낼까 이 대통령이 앞서 일부 현안에 짧게 입장을 밝히기는 했지만 대체로 원론적 언급에 그친 경우가 많았다.  연임 개헌 논란을 두고는 프랑스 국빈방문 중이던 지난 9일(현지시간) 파리 동포 오찬간담회에서 "(대통령) 임기는 헌법상 명확하게 제한돼 있다"고 했다. 취임 초 해외 순방을 자주 다니는 이유를 설명하는 차원의 언급이었지만 연임 논란을 의식한 우회적 입장 표명이라는 해석이다.  공소 취소와 관련해서는 지난 6월 8일 진행한 취임 1주년 회견에서 "(조작기소 여부의) 진상 규명은 해야 한다"는 원론적 답변을 내놨다. 이 대통령은 당시 공소 취소 특검에 대한 질문을 받고 "결론적으로 법과 상식대로 하면 된다"며 "최소한의 진상규명을 해야 한다"고 했다. 이 대통령은 "뭔가 문제는 있어 보인다. 주관적 판단은 있지만 객관적으로도 문제가 있어 보이는 것이 꽤 많다"며 "잘못된 게 있으면 바로 잡고 없으면 그냥 놔두면 된다. 잘못됐으면 취소하고 잘못된 게 아니면 놔두는 것"이라고 했다. 사실상 공소가 잘못됐으면 바로 잡아야 한다는 취지의 설명이었다.  ◆여권에서도 "공소취소·연임 명확한 입장 내야" 목소리 강해   야권뿐 아니라 여권에서도 이 대통령이 민감한 현안에 대해 명확한 입장 표명을 해야 한다는 목소리가 강하다. 장동혁 국민의힘 대표는 이날 최고위원회의에서 "기자회견이 의미가 있으려면 그동안의 오만과 무능부터 국민에게 사과해야 한다"며 "부동산과 이란 파병 문제 등 모든 정책에서 국정 기조 대전환을 선언하고 국민이 납득할 분명한 답을 내놓길 바란다"고 요구했다. 한병도 민주당 원내대표는 정책조정회의에서 "기자회견은 국민 목소리를 경청하고 국정 현안을 두고 진솔한 대화를 나누는 소통의 장이 될 것"이라고 강조했다.  이광재 민주당 의원은 "공소 취소는 정무적이고 정치적인 문제이니 대통령이 언급할 것으로 본다"고 했다. 여권의 한 중진 의원은 "대통령이 연임 개헌이나 공소 취소와 관련해 명확한 입장을 내놓지 않는다면 향후 국정 운영이 쉽지 않을 것"이라고 우려했다.  이재명 대통령이 8일 청와대 영빈관에서 취임 1주년 기자회견을 하고 있다. 2026.06.08 [사진=청와대] ◆9주 연속 지지율 하락…추석 전 기자회견, 반등 할까  이번 기자회견은 추석 연휴를 앞두고 열리는 만큼 지지율 반등의 분수령으로 꼽힌다. 여론조사 전문기관 리얼미터가 14일 공개한 9월 2주차 주간동향(에너지경제신문 의뢰, 7~11일, 무선 자동응답 방식 조사, 표본오차는 95% 신뢰수준에 ±2.0%포인트, 중앙선거여론조사심의위원회 홈페이지 참조)을 살펴보면 이 대통령의 국정수행 긍정평가는 9주 연속 하락해 취임 후 최저치인 33.8%였다. 부정평가는 63.3%로 처음 60%대에 올라섰다. 리얼미터는 외교 행보에도 개각 인선 논란과 호르무즈 파병 검토, 부동산 정책 불확실성이 겹친 데다 진보층과 20대 이탈이 더해진 것을 하락 주요 원인으로 분석했다.  한국갤럽이 17일 발표한 '2026 대한민국 신뢰도 조사'(시사IN 의뢰, 6~8일, 유선전화와 휴대전화 무작위 전화걸기 전화면접조사)에서는 이 대통령이 정치인 중 2위로 내려앉았다. 이 대통령은 2021년 이후 해당 조사에서 줄곧 가장 신뢰하는 정치인 1위였다. 올해 조사에서는 한동훈 무소속 의원에게 1위를 내줬다.  이 대통령에 대한 신뢰도 조사에서는 '신뢰한다' 35.9%, '불신한다' 50.4%였다. 지난해 조사에서는 이 대통령을 신뢰한다는 응답이 51.2%, 불신한다는 응답이 34.1%였다. 신뢰와 불신의 국민 평가가 1년 만에 뒤집어졌다.  the13ook@newspim.com 2026-09-17 14:37
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